Masakazu Isobe Selected Research

CX 659S

11/2003	Structure and activity relationships of novel uracil derivatives as topical anti-inflammatory agents.
6/2003	Inhibitory activity of CX-659S, a novel diaminouracil derivative, against the rebound phenomenon following withdrawal of corticosteroid therapy for chronic contact hypersensitivity responses.
1/2003	The combined effect of topical CX-659S, a novel diaminouracil derivative, with topical corticosteroid on the three types of allergic responses in mice or guinea pigs.

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Masakazu Isobe Research Topics

Disease

5	Contact Dermatitis (Eczema, Contact) 02/2016 - 01/2003
2	Skin Diseases (Skin Disease) 02/2016 - 06/2003
1	Pruritus (Itching) 02/2016
1	Dysgeusia (Parageusia) 12/2012
1	Atopic Dermatitis (Atopic Eczema) 06/2003
1	Hypersensitivity (Allergy) 01/2003

Drug/Important Bio-Agent (IBA)

4	Picryl Chloride (Trinitrochlorobenzene)IBA 11/2003 - 01/2003
3	CX 659SIBA 11/2003 - 01/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2003 - 01/2003
1	oxatomideIBA 02/2016
1	HaptensIBA 02/2016
1	Hydroxyl RadicalIBA 02/2016
1	Biological ProductsIBA 02/2016
1	Substance PIBA 02/2016
1	MicronutrientsIBA 12/2012
1	ZincIBA 12/2012
1	UracilIBA 11/2003
1	SteroidsIBA 06/2003
1	pyrimidineIBA 03/2003
1	OxazoloneIBA 01/2003
1	Dinitrochlorobenzene (DNCB)IBA 01/2003

Therapy/Procedure

1	Oral Administration 02/2016
1	Therapeutics 06/2003
1	Topical Administration 03/2003